Seung-Jung Recreation area, M buy cialis online .D., Duk-Woo Recreation area, M.D., Young-Hak Kim, M.D., Soo-Jin Kang, M.D., Seung-Whan Lee, M.D., Cheol Whan Lee, M.D., Ki-Hoon Han, M.D., Seong-Wook Recreation area, M.D., Sung-Cheol Yun, Ph.D., Sang-Gon Lee, M.D., Seung-Woon Rha, M.D., In-Whan Seong, M.D., Myung-Ho Jeong, M.D., Seung-Ho Hur, M.D., Nae-Hee Lee, M.D., Junghan Yoon, M.D., Joo-Young Yang, M.D., Bong-Ki Lee, M.D., Young-Jin Choi, M.D., Wook-Sung Chung, M.D., Do-Sun Lim, M.D., Sang-Sig Cheong, M.D., Kee-Sik Kim, M.D., Jei Keon Chae, M.D., Deuk-Young Nah, M.D., Doo-Soo Jeon, M.D., Ki Bae Seung, M.D., Jae-Sik Jang, M.D., Hun Sik Park, M.D., and Keun Lee, M.D.: Length of Dual Antiplatelet Therapy after Implantation of Drug-Eluting Stents Several pivotal scientific trials show that the use of drug-eluting coronary stents is usually associated with significant reductions in the risks of restenosis and need for target-lesion revascularization, as compared with use of bare-metallic coronary stents.1 Based on the total results of the trials, drug-eluting stents have already been useful for percutaneous coronary intervention in clinical practice widely.2 However, some longer-term research show that drug-eluting stents, as compared with bare-metal stents, are connected with increased rates of late stent thrombosis, death, or myocardial infarction.3,4 It has been proposed that the occurrence of late clinical events may be due to delayed arterial healing following the implantation of drug-eluting stents.5 Early discontinuation of dual antiplatelet therapy has been defined as a risk factor for late stent thrombosis in patients with drug-eluting stents.6,7 Current PCI guidelines advise that clopidogrel, at a dosage of 75 mg daily, should be given for at least 12 months after implantation of drug-eluting stents if sufferers are not at risky for bleeding.
Randomization was based on a permuted-block style , was stratified regarding to middle and symptomatic status, and was performed after the patient, doctor, and interventionist could request a day for the task within 2 weeks. Stenting and Endarterectomy Carotid-artery carotid and stenting endarterectomy were performed according to published guidelines.9,11,12 For carotid-artery stenting, the process specified usage of the RX Acculink stent and, whenever feasible, the RX Accunet embolic-protection gadget. At least 48 hours before carotid-artery stenting, individuals received aspirin, at a dose of 325 mg daily twice, and clopidogrel at a dosage of 75 mg twice daily.