AKAP protein alterations implicated in bipolar disorder By Lucy Piper, Senior medwireNews Reporter Researchers have found increased cellular expression of the postsynaptic signaling proteins AKAP5/79 in the anterior cingulate cortex of sufferers with bipolar disorder . Their outcomes, published in the Journal of Psychiatric Research, show both an elevated density of neurons expressing the proteins in the ACC and even more pronounced immunostaining of intraneuronal AKAP. These findings fit with recent reports of elevated glutamatergic plasticity and neurotransmission of the ACC in patients with BD, say the researchers, led by Hans-Gert Bernstein, from the University of Magdeburg in Germany http://metronidazole500mg.com .

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