There were no serious catheter-related adverse events in possibly scholarly study group. Discussion Our results do not support the hypothesized superiority of management guided by intracranial-pressure monitoring over management guided by neurologic evaluation and serial CT imaging in patients with severe traumatic brain injury. Intracranial-pressure monitoring may be the cornerstone of treatment for serious traumatic brain injury. The principle guiding additional interventions, like the monitoring of cerebral perfusion pressure or tissue-perfusion modification, may be the maintenance of intracranial pressure below 20 mm Hg. The majority of the data from nonrandomized, controlled trials support the association of treatment based on monitored intracranial pressure with improved recovery, which includes resulted in the recommendation of this approach in successive editions of published recommendations for the management of severe traumatic human brain injury4-7 .