A fantastic 48’X48′ William Claxton piece, ‘Chet Baker , Hollywood, 1954,’ was offered for $90K. The lucky winner of the photograph also surely got to take home Claxton’s Nikon F 35mm Camera along with the ‘Jazz Existence’ trade edition reserve. Guests also experienced the opportunity to bid on a watch from the Elton John Watch Collection designed by Caroline Gruosi-Scheufele. The dazzling limited timepiece was marketed for $90K. Other auction items included an incredible photograph by Robert Mapplethrope called ‘Grace Jones, 1984’ that was sold for $85K and surprised his guests with the opportunity to bid on a 7-time stay for 10 people in Elton’s home in Windsor or Nice and the winners of the bid may also be able to experience the wonderful dishes cooked by Elton’s personal chef.In mouse models of FGFR-powered tumors, daily oral dosing of ponatinib decreased tumor development and inhibited signaling in every 3 FGFR-driven versions examined. Ponatinib reduced tumor development by 80 % in mouse types of bladder and endometrial cancers and induced tumor regression in a model of gastric cancer. Potency was similar compared to that previously observed in BCR-ABL-driven types of chronic myeloid leukemia .